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Metabolism of amino acids: Transaminations

Principle

Specific enzymes for each amino acid, called transaminases, catalyze the transfer of the amino (or ammonium) group from an amino acid to the $ \alpha $ position of an $ \alpha $ -ketocarboxylate

Transaminases are often "aided" by a "co"enzyme, pyridoxalphosphate (PLP, Vitamin B6), which is charged temporarily with the amino group by exchanging it on its aldehyde site:

Special cases of transaminations

Alanine

Aspartic acid